Why is Water is coming from up from my Bathroom sink drain?

This is the only sink having this problem, It is not used much because we keep our dog in the bathroom while we are gone so He does not set off the alarm. He has previously chewed up the sheet rock in the walls, and I do know Baby powder used around that area. There also were a few wash clothes that were old and looked wet and slimy I didn’t notice because they were under a piece of cardboard that was placed up there. Does anyone know what could be wrong or a possible solution?

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